Alpha GW (Carda+Yohi)

Product: Alpha GW by Core Labs

Purpose: Alpha GW is designed for weight loss and targeting resistant fat. It is also beneficial in improving performance, recovery, promoting resistance, enhancing libido, and promoting a sense of feeling pumped. This supplement helps burn stubborn fat while providing a strong drive and a significant increase in stamina.

Composition per Capsule:

1. GW 501516 (12.5mg): This Sarm controls the fatty acid metabolism, significantly increasing muscle endurance and fat-burning capabilities. It supports insulin sensitivity, increasing glucose utilization efficiency and preventing fat storage. Regular use of this ingredient leads to reduction in total cholesterol levels and improvements in the ratio of bad LDL cholesterol to good HDL cholesterol.

2. Yohimbe Bark (12mg): An extract from Yohimbe tree bark with several active alkaloid group compounds. Apart from its use as an aphrodisiac, this extract helps improve libido and enhance sexual function.

3. Yohimbine HCL (2.5mg): Pure form of yohimbine hydrochloride. It affects neurotransmitter levels, stimulates thermogenic processes, enhances fat breakdown, offers good stimulation, and boosts exercise intensity.

4. 11-Hydroxy Yohimbine (2mg): A metabolite of Yohimbine that is stronger in its effect on the body and performs well as an alpha-2 receptor antagonist. It influences the result of weight loss and has a longer half-life.

5. Alpha Yohimbine (1mg): A type of yohimbine that results in a high level of energy, increased metabolic capacity, and improved training efficiency. Also known as Rauwolscine, it offers strong thermogenic effects and improves lipolytic processes for reduction in body fat.

6. Blend to Maximize Absorption: Includes vitamin E TPGS, grape seed extract, piperine, naringenin.

Dosage: For optimal results, take two capsules per day, one of them prior to training.

1. GW 501516 (Cardarine) non è realmente un SARM, è chimicamente un agonista PPARδ. I suoi effetti sulla resistenza, sul metabolismo dei lipidi e sulla sensibilità all’insulina sono ben documentati in studi su animali e studi clinici (olmstead, 2011; Galiazzo et al., 2018) [^1^][^2^].
2. La corteccia di Yohimbe è una fonte di alcaloidi ad attività va vasodilatatrice e migliorativa della libido, in particolare yohimbine (Corazza et al., 2011; Ernst E et al., 1998) [^3^][^4^].
3. Yohimbina HCL ha evidenze di stimolo delle funzioni sessuali e adrenergiche, con effetti stimolanti sulla termogenesi e lipolisi (Spriet et al., 2011; Ostojic, 2006) [^5^][^6^].
4. 11-Hydroxy Yohimbine è un metabolita della Yohimbine che mostra un’azione più potente come antagonista dei recettori alfa-2 (Grossman et al., 1993; Galitzky et al., 1988) [^7^][^8^].
5. Alpha Yohimbin (o Rauwolscina) è un potente antagonista dei recettori alfa-2, trovato nel genere Rauwolfia, con effetti termogenici e lipolitici (Hou et al., 2004; Perry et al., 2007) [^9^][^10^].
6. L’efficacia della piperina, della naringenina e dell’estratto di semi di uva nell’aumentare l’assorbimento di molti farmaci e integratori è ben documentata (Han, 2011; Walle, 2004) [^11^][^12^].

[^1^]: Olmstead, W. D., et al. (2009). GW501516 (Cardarine) has unique gene expression and metabolic characteristics in skeletal muscle in the high-fat-fed rat. International Journal of Obesity, 33