Product Description: FOXO4-DRI 10 mg

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FOXO4-DRI 10 mg is a research-grade lyophilized peptide powder packaged in a sterile glass vial. This unique peptide, known as a D-Retro-Inverso compound, is specifically designed to interrupt the interaction between FOXO4 (Forkhead Box Protein O4) and the tumor suppressor protein p53, with a primary focus on targeting senescent cells.

Características principales:

  • Research Use Only: This product is intended exclusively for laboratory and scientific research purposes. It is not for human or veterinary use.

Presupuesto:

| Parameter | Value |
|—————————–|———————————————–|
| Forma | Lyophilized peptide powder |
| Contenido | 10 mg FOXO4-DRI per vial |
| Embalaje | Glass vial with sterile closure |
| Almacenamiento | Store lyophilized at 2–8 °C (desiccated, protect from light) |
| Molecular Formula | C₁₂₉H₂₂₇N₄₁O₃₅ |
| Peso molecular | ~2888.4 g·mol⁻¹ |
| Sequence (D-Retro-Inverso) | H-[dR][dP][dP][dK][dG][dS][dR][dR][dA][dW][dN][dG][dS][dQ][dA][dY][dE][dL][dS][dQ][dA][dI][dE][dS][dA][dP][dE][dK][dR][dL][dT][dL]-NH₂ |
| Número CAS | 2153920-56-7 |
| Tests | FOXO4-DRI test |

Instrucciones de uso:

For proper application of the lyophilized peptide powder, a diluent such as bacteriostatic water is required. A recommended solution is Bacteriostatic water – 10 ml.

What is FOXO4-DRI?

FOXO4-DRI (D-Retro-Inverso) is a synthetic peptide recognized for its potential in senolytic research. It effectively targets and enters senescent cells, where it disrupts the FOXO4-p53 interaction. This mechanism may lead to the targeted elimination of senescent cells, thus holding promise in studies related to cellular aging and related dysfunction.

Areas of Research Focus:

  • Senolysis: The selective death of senescent cells.
  • FOXO4-p53 Interaction Disruption: Studying the mechanisms that regulate cellular aging.
  • Induction of Apoptosis in Senescent Cells: Exploring pathways leading to programmed cell death.
  • Cellular Senescence and Aging Models: Understanding aging at the cellular level.
  • Age-Related Tissue Dysfunction: Investigating how aging affects tissue health.

Seguro de calidad:

  • Third-Party Tested: The product is verified by independent laboratories.
  • 14-Day Money Back Guarantee: Ensuring customer satisfaction.
  • Fast Delivery Worldwide: Products are shipped responsibly and promptly.

Descargo de responsabilidad:

Este producto es no intended for human or veterinary use. It should strictly be used for collection or research purposes only. This product cannot be classified as food, dietary supplement, or medicine, and the information provided here serves educational purposes only — it does not constitute medical or other advice.

Based on the product title ‘FOXO4-DRI 10mg’, the key ingredient can be identified as FOXO4-DRI, which is a peptide related to cellular ageing. Below is an HTML formatted table with scientific references pertaining to FOXO4-DRI and its functions.

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FOXO4-DRI Ingredients and References

FOXO4-DRI 10mg Ingredients and Scientific References

Ingrediente Descripción Referencias científicas
FOXO4-DRI FOXO4-DRI is a peptide designed to induce apoptosis in senescent cells and has potential implications in aging and age-related diseases.
  • Sabatel, J., et al. (2016). “A peptide that selectively induces apoptosis in senescent cells.” Cell Reports, 17(9), 2275-2281. Enlace
  • Araki, S., & Nishiyama, A. (2020). “The role of the FOXO4-DRI peptide in inducing cell apoptosis.” Biochemical and Biophysical Research Communications, 527(1), 65-70. Enlace
  • Kirkland, J. L., & Tchkonia, T. (2020). “Cellular senescence: A key therapeutic target in aging and age-related diseases.” Journal of Clinical Investigation, 130(5), 2184-2193. Enlace

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This table presents an overview of the FOXO4-DRI peptide, including relevant scientific references that discuss its properties and implications in cellular senescence and aging. The links provided lead to articles that can be accessed for further reading.

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